What is the final stage of lymphoma when the liver or bone marrow are involved?

The final stage of lymphoma is classified as Stage IV when there is involvement of extranodal sites such as the liver or bone marrow. This stage signifies that the disease has spread beyond the original site of the lymphoma, affecting other organs and tissues in the body. In the case of lymphoma, the presence of cancer cells in the liver or bone marrow indicates a more advanced level of disease progression.

Stage IV lymphoma is often associated with more severe symptoms and a poorer prognosis compared to earlier stages, which are limited to localized areas or nearby lymph nodes. This classification is crucial for determining the appropriate treatment plan and assessing the overall outlook for the patient. Recognizing the significance of Stage IV helps in understanding the staging system for lymphomas and the implications for patient care.