Which finding is NOT consistent with significant hypertension in a patient being screened?

The correct answer highlights that a subparietal headache is not typically associated with significant hypertension during a screening process. While headaches can be a symptom of hypertension, they are very nonspecific and can result from a variety of issues unrelated to blood pressure levels. A subparietal headache, which might be indicative of other conditions or causes, does not have a direct and significant correlation with elevated blood pressure as compared to the other listed options.

On the other hand, epistaxis, or nosebleeds, can be a direct consequence of high blood pressure, as the fragile blood vessels in the nasal mucosa can rupture due to increased pressure. Blurred vision can also result from hypertensive retinopathy, where the high blood pressure affects the blood vessels in the eyes, leading to changes in vision. An S4 heart sound indicates increased stiffness of the ventricles, often caused by longstanding hypertension, indicating a heart that is being worked harder due to elevated blood pressure.

These findings—epistaxis, blurred vision, and an S4 heart sound—are more directly related to the physiological impacts of significant hypertension, making a subparietal headache the least consistent sign in this context.